General Cell Lines and Cell Cultures
ATCC Chlamydia trachomatis; Strain: LGV III; DNA
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Farage Lymphoma; Human
Farage is a B lymphocyte cell line that was isolated in 1990 from a White, adult female patient with non-Hodgkin's B Cell lymphoma. This cell line was deposited by H Ben-Bassat and can be used in immunology research.
ACROBiosystems CHO/Human CD32b Stable Cell Line (High Expression) Development Service
Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies.
Lonza Walkersville Human Mesenchymal Stem Cell (hMSC) Osteogenic Differentiation Medium BulletKit
Stem cells possess the unique ability to differentiate into multiple lineages of cells including osteoblasts. Lonza’s hMSC Osteogenic Differentiation BulletKit Medium is a serum containing medium designed to induce osteogenic differentiation of human bone marrow derived mesenchymal stem cells (hMSC) into mature, functionally active osteoblasts in as few as 14 days. Differentiation can then be validated by a variety of methods including the use of Lonza’s OsteoImage Bone Mineralization Reagent which provides a quantitative value related to the amount of osteogenic differentiation.Content:1 x hMSC Osteogenic Differentiation Basal Medium (PT-3924), 170 mL1 x hMSC Osteogenic Differentiation SingleQuots Supplements Kit (PT-4120)
ATCC Quantitative Genomic; RNA from Human; coronavirus 229E
Quantitative genomic RNA from Human coronavirus 229E (ATCC VR-740) can be used for assay development, verification, and validation as well as monitoring of day to day test variation and lot to lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
STEMCELL Technologies Human Peripheral Blood Leukopak, Fresh, undefined: 9 x 10^8 cells minimum
Obtain large numbers of single-donor mononuclear cells (PBMCs) from normal peripheral blood and reduce the time and reagents required for your downstream cell isolation. Enjoy personalized service, custom products, flexible delivery times, and multiple size options. Leukopaks are highly concentrated, low-volume apheresis collections from normal donors, with Institutional Review Board (IRB)-approved consent forms and protocols. Each full-sized leukopak is produced from ~2 - 3x blood volumes using the Spectra Optia Apheresis System (unless otherwise requested), with ACDA as the anticoagulant. High-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Contact techsupport@stemcell.com for more information, including donor selection or information (BMI category, smoking status, ethnicity, etc.). Donors are recallable and are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories.
STEMCELL Technologies Human Whole Peripheral Blood Collected with Sodium Heparin, Fresh, Size: 250 mL
Normal whole peripheral blood (PB) is obtained from healthy donors using Institutional Review Board (IRB)-approved consent forms and protocols. Acid citrate dextrose, solution A (ACDA), Sodium Heparin (Na-Hep), Ethylenediaminetetraacetic acid (EDTA), or Citrate-phosphate-double-dextrose (CP2D) is the anticoagulant.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information and to inquire about donor selection or information including BMI category, smoking status, ethnicity, etc.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
STEMCELL Technologies Human Peripheral Blood CD19+CD27- Naïve B Cells, Frozen, Size: 1 x 10^6 cells
Primary human CD19+ naïve B cells were isolated from peripheral blood (PB) mononuclear cells (MNCs) using negative immunomagnetic separation techniques. PB was collected using acid-citrate-dextrose solution A (ACDA) as the anticoagulant.Cells were obtained using Institutional Review Board (IRB)-approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
ATCC WEHI-3; Leukemia; Mouse (Mus musculus)
WEHI-3 is an animal cell line that was isolated from the peripheral blood of a mouse with leukemia. It has applications in immune system disorder research and immunology.
Eurofins Discoverx Ready-to-Assay A2A Adenosine Receptor Frozen Cells, 2 Vials of Cells. (HTS048LRTA)
The Ready-to-Assay A2A Adenosine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. adenosine, NECA) based activation of ADORA2A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADORA2A alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of ADORA2A, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Escherichia coli; serotype O157:H7
Escherichia coli strain CDC EDL 933 was isolated from raw hamburger meat implicated in a hemorrhagic colitis outbreak. This whole-genome sequenced bacterial strain is serotype O157:H7 and produces Shiga-like toxins I and II.
Innovative Research Inc Synthetic Human Cerebrospinal Fluid (CSF) 25ml
Synthetic Human Cerebrospinal Fluid (CSF) from Innovative Research has been prepared to closely resemble natural CSF. This product is sterile, formulated using high purity water and analytical-grade reagents, and is 0.2 µm filtered. Synthetic CSF does not contain neurotransmitters and electrolyte levels closely match those of natural CSF with final ion concentrations of 150 mM Na, 3.0 mM K, 1.4 mM Ca, 0.8 mM Mg, 1.0 mM P, and 155 mM Cl. The final makeup of this product closely mirrors that of brain interstitial fluid, and the pH can be easily adjusted using HCl or NaOH to meet your exact research application.
This product is useful as a control and can replace human and animal samples for a variety of in vitro applications, including but not limited to measuring CSF absorption, use as a general infusate or perfusate, use as a sterile dilutent, use as a flushing fluid for molecule delivery, and in electrophysiology research to maintain osmolarity and/or buffer pH at physiolog
ATCC Cutaneotrichosporon oleaginosum; Strain: D
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Alkalihalophilus pseudofirmus
Alkalihalophilus pseudofirmus strain DSM 8715 [C324, NCIMB 10283, PN-3] is an alkaliphilic bacterial type strain that was isolated in Germany from lake bank soil.